Peptid-Klartext DE Community
Peptide index

Peptides from A to Z.

21 peptides with approval status, evidence and risks, 18 technical terms explained in plain language – and what vials, pens and syringes look like. No doses, no shop links.

Evidence bars: 1 = cell/animal studies only · 2 = small human studies · 3 = large trials, not yet completed · 4 = large randomised trials and approval. As of September 2026.

Take a look

What it looks like

Schematic drawings so you know what you are holding – and how to spot problems. Real products look different depending on the manufacturer.

The vial – three states

OK

Lyophilisate

White, compact “cake” at the bottom. May be slightly crumbly. Flip-off cap over a rubber stopper, with a metal crimp underneath.

OK

Dissolved

Clear and colourless after dissolving. Let the liquid run down the glass wall and swirl, do not shake.

Do not use

Cloudy or flakes

Cloudiness, streaks, particles or discolouration indicate contamination or degradation. Dispose of it.

Pens, syringes, nasal spray

5

Prefilled pen (disposable)

This is how approved medicines such as tirzepatide or semaglutide come from the pharmacy. The active ingredient is already dissolved, the window shows the solution, and the dose is printed on the label or selected with the button. Multi-dose pens (e.g. KwikPen) contain several weekly doses.

20

Reusable pen with cartridge

Refillable pen with a replaceable 3 mL cartridge and dial. One click usually equals 0.01 mL. Before each use, briefly “prime” it until a drop appears at the needle.

Example of a certified reusable pen: the GensuPen 2 from the Polish manufacturer Bioton – a medical device designed for its Gensulin insulin cartridges (manufacturer’s page). Important: for other, self-filled cartridges the manufacturer does not guarantee accurate dosing. With pens, always look for CE marking as a medical device – many cheap pens from online shops are only declared as “lab tools”.

U-100 insulin syringe

Recognisable by the orange cap. Available in 0.3, 0.5 and 1.0 mL. The scale counts units: 100 units = 1 mL. Use only once.

PC SN LOT EXP

Genuine pharmacy pack

In Germany: German labelling, package leaflet, tamper-evident seal and a DataMatrix code (Securpharm) with a serial number. The pharmacy checks the code against a database before dispensing.

Nasal spray

For peptides such as Semax or Selank. The amount per spray depends on the pump (often 0.1 mL) – this is stated on the pump or pack.

Warning signs when buying

  • “Research use only” or “not for human consumption” on the label
  • No manufacturer, no batch number, no expiry date
  • A pen with a well-known brand name but foreign-language or faulty labelling
  • Damaged cap, missing seal, powder sticking as a film to the glass wall
  • Certificate of analysis without a lab name, without a matching batch – or none at all
Terms

Technical terms explained briefly

Agonist
A substance that binds to a receptor and activates it – like a matching key. GLP-1 agonists, for example, activate the GLP-1 receptor.
Amino acid
Building block of peptides and proteins. There are 20 protein-forming amino acids.
Bacteriostatic water (BAC water)
Sterile water with 0.9% benzyl alcohol. The additive inhibits bacterial growth, so an opened vial can be used several times. Not the same as water for injection.
COA / certificate of analysis
Lab report on the purity and content of a batch. Only meaningful if it comes from an independent lab, matches the batch number and can be verified.
Endotoxins
Components of dead bacteria. Even small amounts in injections can trigger fever and inflammation. Medicines are tested for them, “research” products usually are not.
Evidence
How well an effect is supported. From weak to strong: cell and animal studies → case reports → small human studies → large randomised controlled trials (RCTs).
Half-life
The time it takes for half of an active ingredient to be broken down in the body. Determines how often a medicine is given – for tirzepatide about 5 days, hence once a week.
HPLC / mass spectrometry
Lab methods to check whether the stated substance is really present in the stated purity.
Incretins
Gut hormones such as GLP-1 and GIP that are released after eating, increase insulin release and promote satiety.
Lyophilisate
Freeze-dried powder. Many peptides keep longer in this form than in solution. Typically looks like a white, solid “cake” at the bottom of the vial.
Off-label
Use of an approved medicine outside its approved indication. Only possible under a doctor’s responsibility.
Reconstitution
Dissolving a lyophilisate with a liquid. The amount of liquid determines the concentration – that is what our calculator is for.
Research Use Only (RUO)
Label meaning “for research purposes only, not for human use”. Such products are not subject to the quality requirements for medicines.
Securpharm
The German authenticity verification system: every prescription-only pack in Germany carries a DataMatrix code with a serial number that the pharmacy checks before dispensing.
Subcutaneous (s.c.)
Injection into the fatty tissue under the skin, e.g. on the abdomen, thigh or upper arm. Injection sites should be rotated.
Titration
Gradual dose increase so the body gets used to a medicine – standard with GLP-1 medicines to limit nausea.
U-100
Standard insulin syringes: 100 units = 1 mL, so 1 unit = 0.01 mL. The “unit” here is only a measure of volume.
WADA S0 / S2
Categories of the World Anti-Doping Agency. S0: non-approved substances, S2: peptide hormones, growth factors and related substances. Both are prohibited at all times.