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Regeneration & healing

TB-500: Effects, Evidence and Risks

Also known as thymosin β4 (fragment).

StatusNot approved
EvidencePreclinical
Drug classFragment of thymosin β4

What is TB-500?

Thymosin β4 is a protein made by the body that is involved in cell migration and wound healing. TB-500 is a short synthetic fragment of it.

How well studied is TB-500?

Animal and cell studies on wound healing and heart tissue. There have been small clinical studies with full-length thymosin β4 (e.g. eye drops), but none on TB-500 as an injection.

What are the side effects and risks of TB-500?

Affects cell growth and the formation of new blood vessels – theoretically problematic in cancers (including undiagnosed ones). No long-term data.

Is TB-500 approved in Germany?

In short: no. Not approved. Explicitly banned in sport (WADA S2); there have been doping cases in both horse racing and human sport.

Note: We deliberately list no doses here. For approved medications, your doctor sets the dose; for unapproved substances there is no reliable information.