Peptid-Klartext DE Community
Growth hormone

HGH / somatropin (191 AA): Effects, Evidence and Risks

Also known as Somatropin, recombinant human growth hormone, rhGH, HGH, GH.

StatusApproved (EU)
EvidenceLarge RCTs
Drug classRecombinant peptide hormone (191 amino acids) · injection (subcutaneous)
Add as vial in tracker

We only show doses for approved medicines according to the prescribing information – in the calculator.

What is HGH / somatropin (191 AA)?

Somatropin is genetically engineered human growth hormone, identical to the hormone made by the pituitary. It acts directly and via IGF-1 on growth, metabolism and body composition.

How well studied is HGH / somatropin (191 AA)?

Very well studied and approved for decades: in children with growth disorders (including GH deficiency, Turner syndrome, chronic kidney disease, Prader-Willi syndrome) and in adults with confirmed severe GH deficiency. No benefit has been shown for anti-aging or performance enhancement in healthy people.

What side effects and risks does HGH / somatropin (191 AA) have?

Common effects are fluid retention (e.g. ankles), tingling/numbness, joint and muscle pain and stiffness; blood sugar can also rise. It is contraindicated with active tumours and acute life-threatening illness. Misuse at high amounts can cause acromegaly-like changes and metabolic disorders; counterfeits are widespread on the black market.

Is HGH / somatropin (191 AA) approved in Germany?

In short: yes. Approved in the EU/Germany as a prescription-only medicine (several products, including biosimilars); treatment belongs with specialists. Prohibited in sport (WADA S2); somatropin falls under the German AntiDopG, and trading or possessing non-small amounts for doping is a criminal offence.

Sources

Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.