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Growth hormone

Hexarelin: Effects, Evidence and Risks

Research use only: Hexarelin is not approved as a medicine. It is offered as a research substance labelled “for research purposes only – not for use in humans or animals”. This page summarises the state of research and is not a recommendation to use it.

Also known as Hexarelin, examorelin.

StatusNot approved
EvidenceSmall human studies
Drug classSynthetic hexapeptide, ghrelin receptor agonist (GH secretagogue) · injection
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We only show doses for approved medicines according to the prescribing information – in the calculator.

What is Hexarelin?

Hexarelin is a hexapeptide derived from GHRP-6 that releases growth hormone very strongly via the ghrelin receptor – in humans more strongly than GHRH. It was developed by an Italian manufacturer.

How well studied is Hexarelin?

Hexarelin reached phase II trials for growth hormone deficiency and heart failure but was never fully developed or approved. Human data are limited to small studies of GH release; with continuous use the effect partly wears off (tolerance).

What side effects and risks does Hexarelin have?

Besides GH it also mildly raises prolactin, ACTH and cortisol. Via GH/IGF-1, fluid retention, joint pain and rising blood sugar are possible. Long-term safety is unknown; grey-market products are untested.

Is Hexarelin approved in Germany?

In short: no. Not approved as a medicine anywhere. Prohibited in sport (WADA S2, GH-releasing peptides); may fall under the German AntiDopG. High quality and counterfeit risk.

Sources

Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.