What is Sermorelin?
Sermorelin consists of the first 29 amino acids of the body's own growth hormone-releasing hormone (GHRH). It stimulates the pituitary to release its own growth hormone.
How well studied is Sermorelin?
In the US, sermorelin (Geref) was approved for treating children with idiopathic GH deficiency and for testing GH reserve. There are no solid studies on anti-aging, muscle gain or fat loss in healthy people.
What side effects and risks does Sermorelin have?
Known effects include injection-site reactions, flushing and headache. Via GH/IGF-1, fluid retention and rising blood sugar are possible; stimulating GH is fundamentally problematic with active tumours. Grey-market and “anti-aging” products cannot be verified for purity or content.
Is Sermorelin approved in Germany?
In short: no – only outside the EU. US approval ended in 2008/2009 after the manufacturer withdrew it – according to the FDA not for safety or efficacy reasons. No sermorelin product is approved in the EU/Germany. Prohibited in sport (WADA S2, GHRH analogues); may fall under the German AntiDopG.
Sources
- Federal Register: Determination that GEREF (sermorelin acetate) was not withdrawn for safety or effectiveness
- OPSS: Peptide Hormones as Ingredients in Supplements
Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.