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Longevity & immune system

Humanin: Effects, Evidence and Risks

Research use only: Humanin is not approved as a medicine. It is offered as a research substance labelled “for research purposes only – not for use in humans or animals”. This page summarises the state of research and is not a recommendation to use it.

Also known as Humanin, HN, HNG (humanin-G, synthetic analogue).

StatusNot approved
EvidencePreclinical
Drug classMitochondrially encoded micropeptide or synthetic analogues · research only
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We only show doses for approved medicines according to the prescribing information – in the calculator.

What is Humanin?

Humanin is a small peptide encoded by mitochondrial DNA. In cell experiments it is cytoprotective, including for nerve cells; the synthetic analogue HNG is considerably more potent in the lab.

How well studied is Humanin?

There are cell and animal studies, for example in models of Alzheimer's, stroke and Huntington's disease. In humans there are only observations of blood levels, but no clinical studies of its use.

What side effects and risks does Humanin have?

Nothing is known about side effects in humans. As a cell-protective peptide it could theoretically also promote the survival of unwanted cells – this is unexplored. Grey-market products are untested.

Is Humanin approved in Germany?

In short: no. Not approved anywhere; purely a research compound. In sport, unapproved substances fall under WADA S0. High quality risk with “research peptides”.

Sources

Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.