What is Anastrozole?
Anastrozole inhibits the enzyme aromatase, which converts testosterone to estrogen, thereby lowering estrogen levels. It is approved for treating hormone-sensitive breast cancer in postmenopausal women. In the bodybuilding scene it is used to push down steroid-elevated estrogen and avoid side effects such as gynecomastia or water retention.
How well studied is Anastrozole?
Large randomised trials and approval in breast cancer. There are no registration trials for "estrogen control" during steroid use; the practice is based on anecdotal experience.
What side effects and risks does Anastrozole have?
Loss of bone density and increased fracture risk (osteoporosis) is a central risk. Other possible side effects: joint pain, hot flushes, changes in liver values, chest pain, allergic reactions. In men, estrogen pushed too low can additionally impair libido, mood, blood lipids and bone.
Is Anastrozole approved in Germany?
In short: yes. Approved in the EU/Germany and prescription-only. WADA: S4.1 (aromatase inhibitors) – prohibited at all times. Possession and trafficking for doping purposes can fall under the German Anti-Doping Act (AntiDopG); black-market products are often counterfeit or wrongly dosed.
Sources
- MedlinePlus: Anastrozole
- S4 Hormone and Metabolic Modulators – Anti-Doping Prohibited List (drugs.com)
Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.