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Testolone (RAD-140): Effects, Evidence and Risks

Research use only: Testolon (RAD-140) is not approved as a medicine. It is offered as a research substance labelled “for research purposes only – not for use in humans or animals”. This page summarises the state of research and is not a recommendation to use it.

Also known as RAD140, vosilasarm.

StatusNot approved
EvidencePreclinical
Drug classNon-steroidal selective androgen receptor modulator (SARM) · oral
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We only show doses for approved medicines according to the prescribing information – in the calculator.

What is Testolone (RAD-140)?

RAD-140 is a SARM originally developed for medical uses (including cancer research). In fitness circles it is marketed as a particularly “strong” SARM.

How well studied is Testolone (RAD-140)?

There are no reliable data on muscle building in humans; the evidence comes from animal studies. In humans, RAD-140 is documented mainly through case reports of adverse effects.

What side effects and risks does Testolone (RAD-140) have?

Several case reports of severe cholestatic liver injury with jaundice and itching, sometimes with very high bilirubin levels; in the reported cases it resolved after stopping. Plus suppression of the hormone axis, falling HDL and the heart attack and stroke risk flagged by the FDA.

Is Testolone (RAD-140) approved in Germany?

In short: no. Not approved anywhere and not a dietary supplement. WADA: S1.2, listed by name, prohibited at all times. In Germany, anabolic agents fall under the Anti-Doping Act (AntiDopG): manufacturing, trafficking and placing on the market are criminal offences, as are acquiring and possessing non-small quantities for doping; for elite athletes, self-doping is a criminal offence. The content of online products is uncontrolled.

Sources

Note: We deliberately do not list any doses here. For approved medicines, your doctor sets the dose; for unapproved substances there is no reliable information.